Forecast the impact of switching Construct Regions on cell titer and full capsids, enabling strategic comparisons and rankings.
Predict potential truncation propensities for forward and reverse strands when integrating different regulatory elements.
Identify top-performing candidates through an assessment of their truncation profile, secondary and tertiary structures, CpG island immunotoxicity and gene expression.
Improve safety & yield by reducing truncation from secondary & tertiary structures
Maintain efficacy by reducing CpG islands without altering CG ratio
Reduce manufacturing trial and error with optimized full genome capsids
Fully understand constructs with automated AAV characterization reporting
Enhance constructs to generate de novo designs with the best predicted yield, efficacy and safety characteristics
Predict manufacturing results relating to truncations and other issues